The analyse of DNA markers that matter
Unlock the secrets of your genome with a comprehensive DNA test that tells about your genetic vulnerability to complex diseases, inherited diseases, pharmacological compatibility, personal traits, wellness and ancestry
Who We Are
At DNAlyse, we believe that your genes hold a valuable information about you, for which we provide a comprehensive and advanced DNA report.
Our DNA kit is just a step away from you. Once you provide us your saliva, we will analyse your DNA and create your genetic report.
Do you already have a genetic test from another company, and you want to have a second opinion? Then provide us the raw data and we will create your report without the need to send us saliva.
DNAlyse is present in many countries, as the laboratory work and all algorithmic processing is done in Europe and under European law. We take privacy very seriously and we do not trade our customers’ data.
Please note, the generated reports and data by DNAlyse, are used only for research, educational, and informational use, and not to medical diagnostics, or clinical use, or other use. If any doctors or health professionals are concerned about a particular mutation detected in such reports, they will prescribe a second genetic test for clinical use to confirm these mutations against pathologically confirmed variations.
Methodology
There are 46 chromosomes (22 pairs of autosomes and one pair of sex chromosomes) in every cell nucleus. The XY chromosome is linked to the male sex, whereas the XX chromosome is linked to the female sex. The mitochondria (one of the cell organelles) also contains DNA. There are about 22 000 genes in the human genome.
A genetic variant is when a section of the DNA is altered so that it deviates from the genetic sequence reference. Genetic variations can impact larger sections of the genome, such as substitutions, insertions or deletions of DNA sequence, or they might change a single base (a single nucleotide polymorphism - SNP). Such variations have been found in the human genome and can be linked to pathologies as well as physical characteristics.
Scientific research based on genome-wide association studies (GWAS) and whole genome sequencing (WGS) is being used for defining variants. Such studies compare the genetic sequences of affected with those of healthy humans to identify possible pathological variants.
First, your DNA is extracted from your saliva sample with different laboratory methodologies that guarantee highest possible quality. Then your DNA is attached over a genotyping chip, also known as an array. Consequently, different hybridization & fluorescence techniques are used to determine whether or not a genetic variant exists in the different DNA positions. Large number of variants with high precision and an error rate of less than 1% are analyzed by this methodology. This accuracy is supported by the use of customized Illumina's Global Screening Array (GSA) chip with more than 780 000 markers and Illumina HiScan, which is know to be one of the most powerful and accurate on the market.
The last step involves data analysis by an expert team of geneticists and bioinformaticians. Powerful algorithms and software guarantee, with current techniques, maximum accuracy and report reliability. In addition, your information is constantly updated and improved.
The entire process complies with the strictest security and privacy standards by one of the leading laboratories in Europe. In fact, it is the only laboratory in Europe being capable of processing the high number of samples that are received and processed on a monthly basis.
The laboratory has the following certifications to ensure the highest quality and competence in the analysis:
ISO 17025: Accredited analytical excellence
ISO 13485: Oligonucleotides according to the medical devices standard
GLP: The gold standard for conducting non-clinical safety studies
GCP: Pharmacogenomics services for clinical studies
cGMP: Products and tests according to pharmaceutical and biotechnological requirement
Human Genome & Variants
Reliability
COMPLEX DISEASES (85+)
Complex diseases are caused by a combination of genetic factors, environmental factors and lifestyle. We analyse such genetic factors and provide a health report regarding your vulnerability to develop such conditions.
INHERITED DISEASES (100+)
We analyse genetic variants associated with inherited conditions. Some of these are pathologically recessive and occur only when having two variants being inherited by each parent. If only one variant is present, then such 'carriers' do not have the condition but can transfer it to their children. This health report also investigates pathologically dominant conditions.
PHARMACOLOGICAL COMPATIBILITY (75+)
We analyse your response to certain drugs based on your genetic variants. Do NOT STOP taking any medication, neither change your dose without consulting your doctor.
PERSONAL TRAITS (50+)
WELLNESS (35+)
Physical and wellness-associated traits are caused by a combination of genetic factors, environmental factors and lifestyle. We analyse such genetic factors to provide trait and wellness report regarding your likelihood of developing different traits, as well as the presence or absence of key genetic variants that influence such development.
ANCESTRY
Ethnic and Geographical Origins (53 ethnic groups). Paternal haplogroup. Maternal haplogroup. Percentage of Neanderthal DNA. How ancestry is distributed in different populations and ethnicities.
MORE THAN 440 TEST FEATURES
Separated in clear and straightforward categories. We don`t split them into extra categories to increase the price.
FREE DELIVERY TO YOU
THE MOST RELEVANT DNA TEST
We prefer quality rather than quantity. We don`t repeat same features into different categories only just to make our report looking bigger.
FREE REGULAR UPDATES and FOREVER
Thanks to our most advanced software and by using imputation we provide new features, genetics information and renewed results.
DNA CONNECT
Connect with people through your DNA, such as close or distant relatives.
RAW DNA DATA
In case you got tested elsewhere and you received a report with more distracting text rather than results. No worries, we got you covered. Just provide us with your RAW DNA DATA file and we will provide extra and proper analyse.
Why us?
Contact Us
Connect
info@dnalyse.com