The Product

All-in-One DNA Test

One sample. Six dimensions of insight. 440+ meaningful, clinically relevant features for medical professionals, researchers and institutional clients.

Complex Diseases (85+)

Complex Diseases

Combination of genetic and environmental factors.

1. Cardiovascular Diseases

  • Abdominal aortic aneurysm
  • Angina pectoris
  • Arterial hypertension
  • Atrial fibrillation
  • Coronary heart disease
  • Deep vein thrombosis
  • Heart failure
  • Intracranial aneurysm
  • Myocardial infarction
  • Peripheral arterial disease

2. Respiratory Diseases

  • Asthma
  • Chronic Obstructive Pulmonary Disease (COPD)
  • Allergic rhinitis
  • Nasal polyps

3. Autoimmune Diseases

  • Addison's disease
  • Graves' disease
  • Juvenile idiopathic arthritis
  • Multiple sclerosis
  • Primary Biliary Cirrhosis
  • Rheumatoid arthritis
  • Systemic lupus erythematosus
  • Type 1 diabetes mellitus
  • Vitiligo

4. Neurological Diseases

  • Alzheimer's disease
  • Amyotrophic lateral sclerosis (ALS)
  • Bipolar disorder
  • Depression
  • Migraine
  • Multiple sclerosis
  • Narcolepsy
  • Parkinson's disease
  • Schizophrenia
  • Restless legs syndrome
  • Sensorineural hearing loss

5. Gastrointestinal Diseases

  • Abdominal hernia
  • Barrett's esophagus
  • Chronic kidney disease
  • Crohn's disease
  • Diaphragmatic hernia
  • Diverticulosis/Diverticulitis
  • Gallstones
  • Gastroesophageal reflux disease (GERD)
  • Haemorrhoidal disease
  • Non-alcoholic fatty liver disease (NAFLD)
  • Ulcerative colitis
  • Urolithiasis

6. Cancers

  • Basal cell carcinoma
  • Chronic lymphocytic leukemia
  • Colorectal cancer
  • Cutaneous malignant melanoma
  • Glioblastoma
  • Glioma
  • Lung cancer
  • Multiple myeloma
  • Myeloproliferative neoplasms
  • Neuroblastoma
  • Non-medullary thyroid cancer
  • Oral cavity and oropharyngeal cancer
  • Pancreatic cancer
  • Prostate cancer
  • Squamous cell carcinoma of the skin
  • Testicular germ cell cancer

7. Endocrine and Metabolic Disorders

  • Diabetes mellitus type 2
  • Hyperlipidemia
  • Hypothyroidism
  • Non-toxic multinodular goiter
  • Osteoporosis
  • Non-alcoholic fatty liver disease (NAFLD)

8. Musculoskeletal Disorders

  • Carpal tunnel syndrome
  • Dupuytren's disease
  • Fasciitis
  • General osteoarthritis
  • Osteoarthritis of the hip
  • Osteoarthritis of the knee
  • Gout
  • Juvenile idiopathic arthritis

9. Dermatological Diseases

  • Atopic dermatitis
  • Psoriasis
  • Vitiligo
  • Cutaneous malignant melanoma
  • Basal cell carcinoma
  • Squamous cell carcinoma of the skin

10. Ocular Diseases

  • Age-related macular degeneration
  • Cataracts
  • Keratoconus
  • Macular telangiectasia type 2
  • Open angle glaucoma

11. Urological Diseases

  • Benign prostatic hyperplasia
  • Prostate cancer
  • Urolithiasis

12. Other Diseases / Conditions

  • Chronic kidney disease
  • Headaches
  • Restless legs syndrome
  • Testicular germ cell cancer
Inherited Diseases (100+)

Inherited Diseases

Mutation in a single gene.

Present or absent variant.

Possibility of being a carrier.

Chromosomal and Genetic Syndromes

  • Agenesis of the Corpus Callosum with Peripheral Neuropathy (ACCPN)
  • Bloom syndrome
  • Cowden syndrome
  • Ehlers-Danlos Syndrome (EDS)
  • Familial adenomatous polyposis
  • Li-Fraumeni Syndrome
  • Lynch syndrome
  • Neurofibromatosis type I
  • Peters plus syndrome

Metabolic Disorders

  • Alpha-1 Antitrypsin Deficiency
  • Biotinidase deficiency
  • cblA Type Methylmalonic aciduria
  • cblB Type Methylmalonic aciduria
  • Classical homocystinuria due to CBS deficiency
  • Congenital disorder of glycosylation type 1a (PMM2-CDG)
  • Dihydrolipoamide Dehydrogenase Deficiency
  • Dubin-Johnson syndrome
  • Familial Hypercholesterolemia
  • Familial hyperinsulinism (ABCC8-related)
  • Fanconi Anemia (FANCC-related)
  • Gaucher disease
  • Glutaric Acidemia type 1
  • Glutaric Acidemia type 2
  • Glycogen storage disease type 1A (Von Gierke Disease)
  • Glycogen storage disease type 1B
  • Glycogen storage disease type 3
  • Glycogen storage disease type 5
  • Glycogenosis type 2 or Pompe disease
  • Hereditary fructose intolerance
  • Homocystinuria due to MTHFR deficiency
  • Medium-chain acyl-CoA dehydrogenase deficiency (MCADD)
  • Methylmalonic aciduria due to methylmalonyl-CoA mutase deficiency
  • Mucolipidosis IV
  • Mucolipidosis type II
  • Niemann-Pick disease type A
  • Phenylketonuria
  • Primary hyperoxaluria type 1 (PH1)
  • Primary hyperoxaluria type 2 (PH2)
  • Pyruvate kinase deficiency
  • Refsum disease
  • Salla Disease
  • Short chain acyl-CoA dehydrogenase deficiency (SCADD)
  • Sjögren-Larsson syndrome
  • Tay-Sachs disease
  • Tyrosinemia type I
  • Wilson disease
  • Zellweger syndrome

Blood Disorders

  • Beta Thalassemia
  • Hemophilia A
  • von Willebrand disease

Neurodevelopmental Disorders

  • ARSACS (Autosomal recessive spastic ataxia of Charlevoix-Saguenay)
  • Canavan Disease
  • Congenital muscular alpha-dystroglycanopathy and Walker-Warburg syndrome
  • Congenital myasthenic syndrome
  • Familial dysautonomia (Riley-Day syndrome)
  • Leigh Syndrome, French-Canadian type (LSFC)
  • Leukoencephalopathy with vanishing white matter
  • Neuronal Ceroid-Lipofuscinoses type 1 (PPT1)
  • Neuronal Ceroid-Lipofuscinoses type 3 (CLN3)
  • Neuronal Ceroid-Lipofuscinoses type 5 (CLN5)
  • Neuronal Ceroid-Lipofuscinoses type 6 (CLN6)
  • Neuronal Ceroid-Lipofuscinoses type 7 (MFSD8)
  • Pontocerebellar hypoplasia

Muscle and Movement Disorders

  • Congenital stationary night blindness 1C
  • Hypokalemic Periodic Paralysis
  • Limb-girdle muscular dystrophy

Cardiovascular Disorders

  • Brugada Syndrome
  • Dilated Cardiomyopathy 1A
  • Familial Hypertrophic Cardiomyopathy (HCM)
  • Familial Transthyretin Amyloidosis
  • Malignant Hyperthermia

Metabolic Bone Diseases

  • Hypophosphatasia
  • GRACILE syndrome
  • Maple syrup urine disease type 1B
  • Very long chain acyl-CoA dehydrogenase deficiency (VLCADD)

Visual Disorders

  • Complete achromatopsia (type 2) and Incomplete achromatopsia
  • Retinitis pigmentosa
  • Type 1 Oculocutaneous albinism (tyrosinase negative)
  • Type 2 oculocutaneous albinism (tyrosinase positive)

Hearing Disorders

  • Non-syndromic mitochondrial hearing loss
  • Nonsyndromic Hearing Loss and Deafness, DFNB1
  • Usher syndrome

Cystic and Polycystic Conditions

  • Autosomal recessive polycystic kidney disease
  • Birt-Hogg-Dube syndrome
  • Cystic fibrosis
  • Cystinosis

Dermatological Conditions

  • Junctional Epidermolysis Bullosa
  • Rhizomelic Chondrodysplasia Punctata Type 1

Other Specific Disorders

  • Acute intermittent porphyria
  • Pyridoxine-dependent epilepsy
  • Familial advanced sleep phase syndrome (FASPS)
  • Multiple endocrine neoplasia 2B
Pharmacological Compatibility (75+)

Pharmacological Compatibility

Entry into personalized medicine — "one size doesn't fit all".

How our body reacts to different drugs.

Report on dosage, efficacy and adverse reactions.

Dosage — Analgesics / Anti-inflammatory

  • Celecoxib
  • Ibuprofen

Dosage — Anticoagulants

  • Clopidogrel
  • Warfarin
  • Acenocoumarol, Fenprocoumon
  • Tacrolimus

Dosage — Anticonvulsants

  • Phenytoin
  • Brivaracetam
  • Carbamazepine
  • Clobazam
  • Valproic Acid

Dosage — Antidepressants

  • Amitriptyline
  • Citalopram
  • Clomipramine
  • Desipramine
  • Doxepin
  • Escitalopram
  • Fluoxetine
  • Fluvoxamine
  • Imipramine
  • Nortriptyline
  • Paroxetine
  • Trimipramine
  • Venlafaxine
  • Vortioxetine

Dosage — Antipsychotics

  • Aripiprazole
  • Brexpiprazole
  • Haloperidol
  • Iloperidone
  • Olanzapine
  • Pimozide
  • Quetiapine
  • Risperidone
  • Zuclopenthixol

Dosage — Anxiolytics / Sedatives

  • Diazepam

Dosage — Beta Blockers

  • Metoprolol

Dosage — Statins

  • Atorvastatin
  • Fluvastatin
  • Lovastatin
  • Pitavastatin
  • Pravastatin
  • Rosuvastatin
  • Simvastatin
  • Statins (Dosage and risk of myopathy)

Dosage — Proton Pump Inhibitors

  • Lansoprazole, Dexlansoprazole
  • Omeprazole
  • Pantoprazole

Dosage — Immunosuppressants

  • Methotrexate (in rheumatoid arthritis)
  • Thioguanine, Azathioprine, Mercaptopurine

Dosage — Lipid-Lowering

  • Simvastatin

Dosage — Miscellaneous

  • Amifampridine
  • Atomoxetine
  • Codeine
  • Flecainide
  • Folic acid
  • Tramadol
  • Voriconazole

Adverse Effects — Antibiotics

  • Aminoglycoside antibiotics
  • Floxacillin

Adverse Effects — Antidepressants

  • Amitriptyline
  • Citalopram
  • Clomipramine
  • Desipramine
  • Doxepin
  • Escitalopram
  • Fluoxetine
  • Fluvoxamine
  • Imipramine
  • Nortriptyline
  • Paroxetine
  • Sertraline
  • Trimipramine
  • Venlafaxine
  • Vortioxetine

Adverse Effects — Anticoagulants

  • Warfarin
  • Acenocoumarol, Fenprocoumon

Adverse Effects — Antipsychotics

  • Olanzapine
  • Aripiprazole

Adverse Effects — Antiretrovirals

  • Efavirenz
  • Atazanavir
  • Abacavir

Adverse Effects — Antineoplastics

  • Docetaxel
  • Methotrexate
  • Irinotecan

Adverse Effects — Anti-epileptics

  • Valproic Acid
  • Phenytoin
  • Clobazam

Adverse Effects — Miscellaneous

  • G6PD Deficiency and Adverse Drug Reactions
  • Isoniazid
  • Methotrexate
  • Inhalation anesthetics and succinylcholine
  • Peginterferons alfa-2a -2b and ribavirin
  • Lumacaftor + Ivacaftor (Efficacy)
  • Lumacaftor + Ivacaftor (Adverse effects)

Efficacy — Cystic Fibrosis Treatment

  • Ivacaftor (Efficacy)
  • Lumacaftor + Ivacaftor (Efficacy)

Efficacy — Analgesics / Anti-inflammatory

  • Celecoxib
  • Ibuprofen

Efficacy — Anticoagulants

  • Clopidogrel

Efficacy — Antipsychotics

  • Olanzapine (Efficacy)
  • Aripiprazole

Efficacy — Anxiolytics / Sedatives

  • Diazepam

Efficacy — Antiretrovirals

  • Efavirenz (Efficacy)

Efficacy — Statins

  • Atorvastatin
  • Fluvastatin
  • Lovastatin
  • Pitavastatin
  • Pravastatin
  • Rosuvastatin

Efficacy — Immunosuppressants

  • Methotrexate (in rheumatoid arthritis)
  • Thioguanine, Azathioprine, Mercaptopurine

Efficacy — Lipid-Lowering

  • Statins (Dosage and risk of myopathy)
  • Simvastatin

Efficacy — Miscellaneous

  • Amifampridine
  • Atomoxetine
  • Codeine
  • Flecainide
  • Tramadol
  • Voriconazole
Personal Traits (50+)

Personal Traits

Physical and well-being traits are caused by a combination of genetic factors, environmental factors and individual lifestyle.

Hair

  • Hair color
  • Hair texture
  • Male baldness
  • Probability of having red hair

Skin

  • Acne vulgaris
  • Skin melanin levels
  • Facial aging
  • Eye clarity

Body Structure

  • Height
  • Nasion prominence

Facial and Eye Features

  • Pigmented rings on the iris

Handedness

  • Left-handedness (left lateral)

Behavioral

  • Alcohol dependence after prolonged consumption
  • Nicotine dependence after prolonged consumption
  • Neuroticisms
  • Risk tendency

Cognitive

  • Cognitive ability
  • Mental agility

Metabolism

  • Basal metabolic rate
  • Metabolizer profile CYP2C19
  • Metabolizer profile CYP2C9
  • Metabolizer profile CYP2D6
  • Metabolizer profile CYP3A5
  • Heat production in response to cold

Circadian Rhythm

  • Morning circadian rhythm (Morning person)
  • Sleep duration
  • Insomnia

Hormonal

  • Sex hormone regulation (SHBG)
  • Thyroid function (TSH levels)
  • PSA (Prostate Specific Antigen) Levels

Sensory — Smell & Taste

  • Asparagus odor detection
  • Smell

Sensory — Other

  • Photic sneeze reflex

Genetic Variants

  • Gene COMT
  • Gene MTHFR
  • Gene MTR
  • Gene MTRR

Epigenetic

  • Epigenetic aging

Immunity and Blood Traits

  • Blood Group ABO/Rh
  • CCR5Delta32 and susceptibility to HIV infection
  • Duffy Antigen, malaria resistant
  • HLA-B27 antigen
  • C-reactive protein levels

Disease Risk

  • Blood coagulation, factor V Leiden and 20210G-A
  • QT Intervals
  • Permanent tooth eruption
  • Dental caries and periodontitis
  • Mouth ulcers
  • Probability of snoring

General Health Indicators

  • Birth weight
  • Persistence of fetal hemoglobin
  • Secretor status and ABH antigens (FUT2 gene)

Unique or Rare Traits

  • Ear lobe type
  • Earwax type / Armpit odor
  • Asparagus odor detection
  • Photic sneeze reflex
Wellness (35+)

Wellness

Items related to metabolization of macronutrients, vitamin synthesis capacity and muscle regeneration capacity after exercise.

How to adapt lifestyle and diet.

Vitamin and Nutrient Levels

  • Levels of vitamin A (beta carotene)
  • Vitamin B12 levels
  • Vitamin C levels
  • Vitamin D levels
  • Vitamin E levels
  • Long-chain omega fatty acids levels
  • Glycated hemoglobin levels

Taste and Food Preferences

  • Bitter taste perception
  • Preference for sweets

Food Intolerances

  • Lactose intolerance
  • Histamine intolerance
  • Celiac disease predisposition
  • Genetic predisposition to peanut allergy

Metabolism and Body Composition

  • Body mass index
  • Blood glucose
  • Prediction of visceral adipose tissue

Blood Pressure

  • Systolic blood pressure levels
  • Diastolic blood pressure levels

Cholesterol Levels

  • HDL cholesterol levels
  • LDL cholesterol levels

Blood Antioxidants and Circulation

  • Antioxidant capacity
  • Intraocular pressure

Muscle and Tendon Health

  • Exercise-induced muscle damage (initial phase)
  • Exercise-induced muscle damage (second phase)
  • Exercise-induced muscle damage (regeneration capacity)
  • Muscle endurance
  • Tendinopathies in lower extremities (legs)
  • Tendinopathies in upper extremities (arms)
  • Myoadenylate deaminase (AMPD1 gene)

Caffeine and Physical Performance

  • Caffeine and sports performance
  • Caffeine dependence after prolonged consumption
  • Caffeine and anxiety

Respiratory Health

  • Lung function (exhaled air volume)

Bone Health

  • Bone mineral density

Behavioral Predispositions

  • Food intake control
  • Farmer-hunter profile
  • Caffeine dependence after prolonged consumption
Ancestry

Ancestry

Origins & Heritage

  • Ethnic and Geographical Origins (53 ethnic groups)
  • Paternal haplogroup
  • Maternal haplogroup
  • Percentage of Neanderthal DNA
  • How ancestry is distributed in different populations and ethnicities